Programs & Services
TRT & BHRT
Hormone optimization, built on data — not guesswork.
Hormones influence energy, body composition, mood, sleep, libido, and long-term health. Our TRT and BHRT program pairs comprehensive lab work and independent physician evaluation with the nutrition and training coaching that determines whether hormone therapy actually works.
Straight Answers
What is TRT?
TRT (testosterone replacement therapy) restores testosterone toward an optimal physiologic range in men with clinically low levels confirmed by both lab testing and symptoms. It is a medical therapy that requires physician evaluation, ongoing monitoring, and follow-up labs — at BioSphere, all of that is directed independently by licensed physicians of BioSphere Physician Partners, PC.
What is the difference between TRT and BHRT?
TRT specifically replaces testosterone. BHRT (bioidentical hormone replacement therapy) uses hormones structurally identical to those your body makes — estradiol, progesterone, testosterone, DHEA, and thyroid support — and is most often used for perimenopausal and menopausal women, or for men who need broader endocrine support beyond testosterone alone.
How much does hormone optimization cost?
BioCore™ strategy membership starts at $99/month with a Human Optimization Strategist™, personalized strategy, app access, and progress tracking. BioPerformance™ is $299/month and adds nutrition and fitness plans with monthly strategy sessions. Biomed Essential is $299/month, includes BioCore Plus™ coaching and healthcare navigation, and offers a hormone optimization program through BioSphere Physician Partners, PC. Medications and any services not included in the selected membership are billed separately.
Who is a candidate for hormone therapy?
Candidacy is determined by a licensed physician using a full panel — total and free testosterone, estradiol, SHBG, LH/FSH, thyroid, CBC, and cardiometabolic markers — alongside your symptoms and history. Symptoms alone are not a diagnosis, and many people improve substantially by correcting sleep, body composition, alcohol, and protein intake first.
Education
Understanding hormone optimization
What TRT is
Testosterone replacement therapy restores testosterone toward an optimal physiologic range in men with clinically low levels confirmed by lab testing and symptoms. It is a medical therapy requiring evaluation, monitoring, and follow-up labs.
What BHRT is
Bioidentical hormone replacement therapy uses hormones structurally identical to those the body produces — commonly estradiol, progesterone, testosterone, and thyroid support — most often for perimenopausal and menopausal women, and for men needing broader endocrine support.
Why labs come first
A full panel establishes your baseline: total and free testosterone, estradiol, SHBG, LH/FSH, thyroid panel, DHEA-S, CBC, CMP, lipids, ApoB, and hs-CRP. Symptoms alone are not a diagnosis.
Why lifestyle changes the outcome
Sleep debt, visceral fat, alcohol, undereating protein, and chronic stress all suppress hormone signaling. Many people improve substantially before any therapy — and everyone on therapy does better with these fundamentals handled.
Monitoring matters
Ongoing therapy requires periodic labs to track hematocrit, estradiol, PSA where appropriate, and cardiometabolic markers. Your strategist keeps the schedule; your physician interprets and adjusts.
Realistic expectations
Changes in energy and libido often show earlier than changes in body composition. Results vary by individual, and no outcome is guaranteed.
Metrics We Track
Always Included
Every program includes coaching and physician oversight
Personalized nutrition and fitness plans come with BioPerformance™, which is included with BioSphere Concierge. Biomed Essential includes BioCore Plus™ advanced coaching and healthcare navigation; ask about additional nutrition and exercise support for your selected program.
Nutrition Coaching
A certified nutrition coach builds a practical eating strategy around your labs, body composition, and real life — not a generic meal plan.
Exercise Coaching
A personal trainer programs strength, conditioning, and mobility work that matches your capacity and progresses as your data improves.
Physician Oversight
Licensed physicians of BioSphere Physician Partners, PC independently review your case and direct any medical evaluation or treatment.
Human Optimization Strategist™
One dedicated strategist coordinates your team, keeps the plan moving, and translates your data into weekly action.
General Information
General information on possible protocols
Educational overview only. Any medical protocol is prescribed at the independent discretion of a licensed physician after evaluation — not by BioSphere coaching staff.
Male hormone protocols
Physicians may consider injectable, topical, or pellet testosterone, with adjunct agents such as hCG or an aromatase inhibitor where clinically indicated. Route, dose, and cadence are entirely a clinician decision.
Female hormone protocols
Options may include transdermal estradiol, oral or topical progesterone, low-dose testosterone, and DHEA — selected based on menopausal status, symptoms, history, and labs.
Thyroid and adrenal support
Where testing supports it, physicians may address thyroid function or cortisol rhythm, since these often drive symptoms mistaken for low sex hormones.
Coaching layer
Protein-forward nutrition, progressive resistance training, sleep architecture work, and alcohol reduction — the levers that consistently amplify hormone therapy results.
Medical Access Through Partnership
Access to medical evaluation, labs, and prescription protocols is provided through our partnership with BioSphere Physician Partners, PC. Biosphere Human Optimization provides non-medical coaching, education, and coordination. All diagnoses, prescriptions, and treatment decisions are made independently by licensed clinicians. Medical programs have their own membership fees; medications, outside testing, and services not included in a selected membership may be billed separately.
Who this is for
- Men with symptoms of low testosterone confirmed by lab testing
- Women navigating perimenopause or menopause who want a structured, data-driven approach
- People already on hormone therapy who feel under-monitored or under-coached
- Anyone who wants lifestyle fundamentals optimized before considering therapy
How memberships work
Strategy memberships cover coaching, education, tracking, and coordination. Physician-led memberships include the listed medical services and bundled coaching, delivered separately by BioSphere Physician Partners, PC.
BioCore™ · $99/mo
Dedicated strategist, personalized health strategy, app access, and progress tracking.
BioPerformance™ · $299/mo
Everything in BioCore, plus nutrition and fitness plans, monthly strategy sessions, and priority support.
Biomed Essential · $299/mo
Choose a physician-led program; includes BioCore Plus coaching and healthcare navigation.
BioSphere Concierge · BioPrimary™ · $599/mo
Concierge physician services and a coordinated health team; includes BioPerformance multidisciplinary coaching.
BioElite · Executive Health Office™ · $1,999/mo
Executive health leadership team and BioPerformance coaching.
Start with a conversation
Book a session with a Human Optimization Strategist™ to review your goals, your data, and which path fits.
Biosphere Human Optimization provides non-medical coaching and coordination services. It does not diagnose, treat, or prescribe. Medical services are provided independently by licensed clinicians of BioSphere Physician Partners, PC.